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Our laboratory closes for the holidays on 24th December and will reopen on Friday 3rd January 2025.
Our laboratory closes for the holidays on 24th December and will reopen on Friday 3rd January 2025.

Hereditary Nasal Parakeratosis

Turnaround: 1-2 weeks

Original price £48.00 - Original price £48.00
Original price
£48.00
£48.00 - £48.00
Current price £48.00

Hereditary Nasal Parakeratosis (HNPK) causes a dry, rough, and crusty nose which can sometimes crack painfully. Affected dogs are otherwise healthy but the must be continually treated to prevent excessive dryness.

An autosomal recessive condition caused by a mutation in the SUV39H2 gene.

Description

Scientific references

Jagannathan V, Bannoehr J, Plattet P, Hauswirth R, Drögemüller C, Drögemüller M, Wiener DJ, Doherr M, Owczarek-Lipska M, Galichet A, Welle MM, Tengvall K, Bergvall K, Lohi H, Rüfenacht S, Linek M, Paradis M, Müller EJ, Roosje P, Leeb T. A mutation in the SUV39H2 gene in Labrador Retrievers with hereditary nasal parakeratosis (HNPK) provides insights into the epigenetics of keratinocyte differentiation. PLoS Genet. 2013;9(10):e1003848