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Our laboratory closes for the holidays on 24th December and will reopen on Friday 3rd January 2025.
Our laboratory closes for the holidays on 24th December and will reopen on Friday 3rd January 2025.
Haemophilia

Haemophilia

Turnaround: 1-2 weeks

£48.00 - £48.00
£48.00
£48.00 - £48.00
£48.00

Haemophilia (FD), or Coagulation Factor Deficiency, is a disorder which affects normal blood clotting and causes haemophilia. Affected dogs can have a normal life, but it should be noted in case of trauma or surgery which could cause excessive bleeding.

An autosomal recessive condition caused by a mutation in the F7 gene (Factor VII Deficiency), or an X-linked recessive condition caused by a mutation in the F8 (Haemophilia A) or F9 (Haemophilia B) gene.

Description

Scientific references

Callan MB, Aljamali MN, Margaritis P, Griot-Wenk ME, Pollak ES, Werner P, Giger U, High KA. A novel missense mutation responsible for factor VII deficiency in research Beagle colonies. J Thromb Haemost. 2006 Dec;4(12):2616-22

Christopherson PW, Bacek LM, King KB, Boudreaux MK. Two novel missense mutations associated with hemophilia A in a family of Boxers, and a German Shepherd dog. Vet Clin Pathol. 2014 Sep;43(3):312-6