Haemophilia

Our DNA test for Haemophilia is ideal for breeders and owners who want the reassurance of genetic health testing.

The guideline turnaround time for single tests is approximately 10-12 working days after the swab arrives at the lab. 

If you need more than two tests it is often more cost-effective to order the relevant breed package.

Description

Haemophilia (FD), or Coagulation Factor Deficiency, is a disorder which affects normal blood clotting and causes haemophilia. Affected dogs can have a normal life, but it should be noted in case of trauma or surgery which could cause excessive bleeding.

An autosomal recessive condition caused by a mutation in the F7 gene (Factor VII Deficiency), or an X-linked recessive condition caused by a mutation in the F8 (Haemophilia A) or F9 (Haemophilia B) gene.

Breeds

This test is also included in the following breed packages:

• Beagle  (Factor VII Deficiency)
• German Shepherd  (Haemophilia A - FVIIID)
• German Wirehaired Pointer  (Factor VII Deficiency)
• Giant Schnauzer  (Factor VII Deficiency)
• Papillon  (Factor VII Deficiency)
• Rhodesian Ridgeback  (Haemophilia B - FIXD)
• Schnoodle  (Factor VII Deficiency)
• Sealyham Terrier  (Factor VII Deficiency)

Scientific references:

Callan MB, Aljamali MN, Margaritis P, Griot-Wenk ME, Pollak ES, Werner P, Giger U, High KA. A novel missense mutation responsible for factor VII deficiency in research Beagle colonies. J Thromb Haemost. 2006 Dec;4(12):2616-22

Christopherson PW, Bacek LM, King KB, Boudreaux MK. Two novel missense mutations associated with hemophilia A in a family of Boxers, and a German Shepherd dog. Vet Clin Pathol. 2014 Sep;43(3):312-6