Skip to content
Our laboratory closes for the holidays on 24th December and will reopen on Friday 3rd January 2025.
Our laboratory closes for the holidays on 24th December and will reopen on Friday 3rd January 2025.

I-Locus (intensity)

Turnaround: 1-2 weeks

Original price £30.00 - Original price £30.00
Original price
£30.00
£30.00 - £30.00
Current price £30.00

The I-Locus is a region of your dog's DNA which controls the intensity of colour of the phaeomelanin or yellow/red pigment which is expressed through the E-locus.

Your dog's coat colour intensity will only be affected if your dog is e/e on the E-Locus and thus expressing the yellow coat pigment.

The coat colour intensity is affected by mutations on the MFSD12 gene.

 

 

Description

Scientific references

Hédan B, Cadieu E, Botherel N, Dufaure de Citres C, Letko A, Rimbault M, Drögemüller C, Jagannathan V, Derrien T, Schmutz S, Leeb T, André C. Identification of a Missense Variant in MFSD12 Involved in Dilution of Phaeomelanin Leading to White or Cream Coat Color in Dogs. Genes (Basel). 2019 May 21;10(5):386